SCHEMBL7793838

SCHEMBL7793838

Clc1cccc2c(Cl)cc[c]c12

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.52
CYP2A6 P11509 3/20 0.52
NR4A2 P43354 2/20 0.41
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
NOS1 P29475 1/20 0.32
DAO P14920 1/20 0.32
ADRA2A P08913 1/20 0.32
CHEK1 O14757 1/20 0.31
FLT3 P36888 1/20 0.31
PLK3 Q9H4B4 1/20 0.31
PARP1 P09874 1/20 0.31
TYMS P04818 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1193110 0.84 CYP2A6 (0.48) CYP1A2CYP2A6NR4A2LMNATYMS
SCHEMBL29629127 0.71 CYP1A2 (1.00) CYP1A2CYP2A6NR4A2TSHRLMNA
SCHEMBL2468811 0.71 CYP1A2 (1.00) CYP1A2CYP2A6NR4A2TSHRLMNA
SCHEMBL5602251 0.70 CYP1A2 (0.42) CYP1A2CYP2A6NR4A2KMT2A
SCHEMBL457356 0.70 CYP1A2 (0.41) CYP1A2CYP2A6TSHRLMNANOS1
SCHEMBL307862 0.70 CYP2A6 (0.48) CYP1A2CYP2A6NR4A2TSHRLMNA
SCHEMBL16586070 0.70 CYP1A2 (0.54) CYP1A2CYP2A6NR4A2TSHRLMNA
SCHEMBL17698449 0.70 CYP1A2 (0.54) CYP1A2CYP2A6NR4A2TSHRLMNA
SCHEMBL7081918 0.68 CYP1A2 (0.41) CYP1A2CYP2A6
SCHEMBL638983 0.68 CYP1A2 (0.52) CYP1A2CYP2A6NR4A2TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed