Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17520513 | 0.76 | ABCB1 (0.39) | ABCB1 | |
| SCHEMBL20047228 | 0.68 | BRD4 (0.33) | — | |
| SCHEMBL783284 | 0.68 | OPRM1 (0.35) | OPRM1KCNH2SIGMAR1 | |
| SCHEMBL5691663 | 0.66 | — | — | |
| SCHEMBL1363669 | 0.66 | — | — | |
| SCHEMBL17774455 | 0.66 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL13434962 | 0.66 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL9300336 | 0.64 | SMN1; SMN2 (0.48) | SMN1; SMN2 | |
| Enniatin B SCHEMBL16242889 | 0.64 | ABCB1 (0.36) | ABCB1 | |
| Enniatin B SCHEMBL380354 | 0.64 | ABCB1 (0.36) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619732-B1 | BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION | MASSACHUSETTS INST TECHNOLOGY (US) | 2001-01-31 | — | — | EP | disclosed |
| US-5399665-A | Reacting an alpha-amino acid with an alpha-hydroxy acid to form a morpholinedione, polymerizing morpholinedione with Lewis acid; biologically active moieties may be coupled to the polymer | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0619732-A4 | BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION. | MASSACHUSETTS INST TECHNOLOGY (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0619732-A1 | BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1994009760-A1 | BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1994-05-11 | — | — | WO | disclosed |