Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545075 | 1.00 | TSHR (0.41) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9915100 | 0.88 | TSHR (0.48) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7794232 | 0.85 | TSHR (0.39) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7800118 | 0.85 | TSHR (0.39) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28328694 | 0.82 | TRPA1 (0.44) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11763508 | 0.81 | TSHR (0.41) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28379863 | 0.81 | TSHR (0.41) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13672302 | 0.81 | TSHR (0.41) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10631641 | 0.81 | SLC1A3 (0.46) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11448991 | 0.81 | TSHR (0.41) | TSHRIDO1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796248-B1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | WESTERN THERAPEUTICS INST D (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-6143763-A | Carbostyril derivatives | D. WESTERN THERAPEUTICS INSTITIUTE (JP) | 2000-11-07 | — | — | US | disclosed |
| CN-1172478-A | Quinolone derivative antithrombotic agent | OTSUKA PHARMA CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |
| EP-0796248-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| WO-1997012869-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-10 | — | — | WO | disclosed |
| US-4518531-A | Allylic chlorination process and compounds prepared thereby | ELI LILLY AND COMPANY (US) | 1985-05-21 | — | — | US | disclosed |
| US-4430268-A | Allylic chlorination process | ELI LILLY AND COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| EP-0019387-A1 | Thiazolinoazetidinone compounds useful as intermediates for preparing cephalosporins and a process for their preparation | ELI LILLY AND COMPANY (US) | 1980-11-26 | — | — | EP | disclosed |