Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675215 | 0.89 | — | — | |
| SCHEMBL11456995 | 0.89 | — | — | |
| SCHEMBL10457293 | 0.89 | — | — | |
| SCHEMBL25333018 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| Bicarbonate SCHEMBL8900312 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL3503306 | 0.80 | TSHR (0.61) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL32684929 | 0.80 | TSHR (0.61) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL2552092 | 0.80 | TSHR (0.61) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL2989833 | 0.80 | TSHR (0.61) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL2552093 | 0.80 | TSHR (0.61) | ALDH1A1TSHRTDP1ALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905118-B1 | Unsaturated 6-tert-butyl-1,1-dimethylindane derivates substituted in the 4-position and their use in human and veterinary medicine as well as in cosmetics | GALDERMA RES & DEV (FR) | 2001-08-16 | — | — | EP | disclosed |