SCHEMBL7794416

SCHEMBL7794416

CC(=O)Oc1ccc(C(=O)Oc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.76
ELANE P08246 1/20 0.61
GAA P10253 3/20 0.54
LMNA P02545 2/20 0.54
MAPT P10636 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
PARP10 Q53GL7 1/20 0.53
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 3/20 0.50
PKM P14618 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 1/20 0.50
TSHR P16473 1/20 0.50
RAB9A P51151 1/20 0.50
MEN1 O00255 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ESR1 P03372 1/20 0.49
PGR P06401 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9389790 1.00 HSD17B10 (0.76) HSD17B10ELANEGAALMNAMAPT
SCHEMBL9760675 0.92 ELANE (0.64) HSD17B10ELANELMNAMAPTTDP1
SCHEMBL8850878 0.92 ELANE (0.64) HSD17B10ELANELMNAMAPTTDP1
SCHEMBL40184 0.92 HSD17B10 (0.88) HSD17B10ELANEGAALMNAMAPT
Hydrochloric Acid SCHEMBL1374059 0.90 HSD17B10 (0.85) HSD17B10ELANEGAALMNAMAPT
SCHEMBL7026750 0.90 HSD17B10 (0.85) HSD17B10ELANEGAALMNAMAPT
Methane SCHEMBL7956977 0.90 HSD17B10 (0.85) HSD17B10ELANEGAALMNAMAPT
SCHEMBL4597931 0.90 PARP10 (0.62) HSD17B10MAPTTDP1CA1CA2
SCHEMBL7536846 0.90 PARP10 (0.62) HSD17B10MAPTTDP1CA1CA2
SCHEMBL376498 0.90 PARP10 (0.62) HSD17B10MAPTTDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60199859-A None JP disclosed
EP-0887399-B1 Silicones having a low glass transition temperature CONSORTIUM ELEKTROCHEM IND (DE) 2001-11-28 EP disclosed
US-6040411-A Low glass temperature organosiloxanes CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2000-03-21 US disclosed
EP-0887399-A1 Silicones having a low glass transition temperature Consortium für elektrochemische Industrie GmbH (DE) 1998-12-30 EP disclosed
JP-S60199859-A P-HYDROXYBENZOIC ACID DERIVATIVE YOSHITOMI PHARMACEUT IND LTD 1985-10-09 JP disclosed