SCHEMBL9760675

SCHEMBL9760675

CC(=O)Oc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OC(C)=O)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.64
HSD17B10 Q99714 2/20 0.62
LMNA P02545 2/20 0.61
MAPT P10636 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
PKM P14618 2/20 0.55
POLB P06746 1/20 0.55
PARP10 Q53GL7 1/20 0.55
KMT2A Q03164 5/20 0.55
MEN1 O00255 2/20 0.55
ESR1 P03372 1/20 0.55
PGR P06401 1/20 0.55
CHRM2 P08172 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
AR P10275 1/20 0.55
CHRM1 P11229 1/20 0.55
SLC6A2 P23975 1/20 0.55
SLC6A3 Q01959 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8850878 1.00 ELANE (0.64) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL12332649 0.94 HSD17B10 (0.72) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL9735377 0.92 ELANE (0.56) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL14484261 0.92 LMNA (0.77) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL16429666 0.92 ELANE (0.72) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL13503146 0.92 LMNA (0.66) ELANEHSD17B10LMNAMAPTPARP10
SCHEMBL11583538 0.92 LMNA (0.77) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL14370320 0.92 LMNA (0.66) ELANEHSD17B10LMNAMAPTPARP10
SCHEMBL14407747 0.92 LMNA (0.66) ELANEHSD17B10LMNAMAPTPARP10
SCHEMBL14370322 0.92 LMNA (0.77) ELANEHSD17B10LMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 US disclosed
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 US disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 US disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 US disclosed
US-8309632-B2 Liquid crystalline epoxy nanocomposite material and application thereof NATIONAL TAIWAN UNIVERSITY (TW) 2012-11-13 US disclosed
US-20110009521-A1 Liquid crystalline epoxy nanicomposite material and application thereof NATIONAL TAIWAN UNIVERSITY (TW) 2011-01-13 US disclosed
US-5037938-A For preparation of high strength oxidation and thermal chemical resistance, stiffness, low inflammability THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed
EP-0399349-A2 Melt processable thermotropic aromatic copolyesters and process for preparing same THE DOW CHEMICAL COMPANY (US) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009521-A1 Liquid crystalline epoxy nanicomposite material and application thereof NUP205, CNP, NOS2 ELANE 408/4885HSD17B10 2903/4885LMNA 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.