SCHEMBL7794429

SCHEMBL7794429

COCC(=O)Nc1ccc(S(N)(=O)=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 11/20 0.69
CA2 P00918 11/20 0.69
CA9 Q16790 7/20 0.69
CA12 O43570 6/20 0.69
CA7 P43166 2/20 0.67
CA4 P22748 2/20 0.67
KMT2A Q03164 3/20 0.66
MEN1 O00255 2/20 0.66
CA14 Q9ULX7 2/20 0.63
MAPT P10636 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.61
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10296108 0.85 KMT2A (0.68) KMT2AMAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL14962804 0.84 HPGD (0.81) KMT2AMEN1MAPTSMN1; SMN2ALDH1A1
SCHEMBL8815677 0.83 KMT2A (0.61) CA1CA2CA9CA12KMT2A
SCHEMBL13263684 0.81 CA1 (1.00) CA1CA2CA9CA12CA7
SCHEMBL18719854 0.81 CA1 (0.70) CA1CA2CA9CA12CA7
SCHEMBL2000416 0.81 STAT3 (0.74) CA1CA2CA9CA12CA7
SCHEMBL15798365 0.81 SMN1; SMN2 (0.76) CA1CA2CA9CA12KMT2A
SCHEMBL7130773 0.80 CA1 (1.00) CA1CA2CA9CA12CA7
SCHEMBL15335309 0.80 CA1 (0.68) CA1CA2CA9CA12CA7
SCHEMBL24355560 0.80 MEN1 (0.81) CA1CA2CA9CA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912089-B1 NOVEL N-ACYL SULPHONAMIDES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THEIR USE AVENTIS CROPSCIENCE GMBH (DE) 2001-11-28 EP disclosed
US-6235680-B1 REDUCING SIDE EFFECT OF PESTICIDE HOECHST SCHERING AGREVO GMBH (DE) 2001-05-22 US disclosed
EP-0912089-A1 NOVEL N-ACYL SULPHONAMIDES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THEIR USE Hoechst Schering AgrEvo GmbH (DE) 1999-05-06 EP disclosed
WO-1997045016-A1 NOVEL N-ACYL SULPHONAMIDES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THEIR USE HOECHST SCHERING AGREVO GMBH (DE) 1997-12-04 WO disclosed