Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 10/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795596 | 0.93 | GHSR (0.81) | GHSRAGTR1XIAPSCN9ANPY1R | |
| SCHEMBL7785884 | 0.92 | GHSR (0.59) | GHSRAGTR1XIAPSCN9ANPY1R | |
| SCHEMBL7796023 | 0.92 | GHSR (0.81) | GHSRAGTR1XIAPSCN9APTGER1 | |
| SCHEMBL7786005 | 0.92 | GHSR (0.82) | GHSRAGTR1XIAPSCN9APTGER1 | |
| SCHEMBL7794419 | 0.91 | GHSR (0.58) | GHSRAGTR1XIAPSCN9A | |
| SCHEMBL7791724 | 0.91 | GHSR (0.71) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7786112 | 0.90 | GHSR (0.57) | GHSRAGTR1XIAPSCN9A | |
| SCHEMBL7791986 | 0.89 | GHSR (0.85) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7791996 | 0.88 | GHSR (0.69) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL7791702 | 0.88 | GHSR (0.69) | GHSRAGTR1XIAPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | claimed |
| US-5968924-A | HAVE THE ABILITY TO STIMULATE THE RELEASE OF NATURAL OR ENDOGENOUS GROWTH HORMONE; TREATMENT OF OBESITY, OSTEOPOROSIS | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |