Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790405 | 0.90 | MEN1 (0.64) | KMT2AMEN1MMP14POLBMAPT | |
| SCHEMBL8426998 | 0.87 | MEN1 (0.65) | KMT2AMEN1MMP14POLBMAPT | |
| SCHEMBL4286784 | 0.85 | MEN1 (0.52) | KMT2AMEN1MMP14POLBMAPT | |
| SCHEMBL11707400 | 0.83 | POLB (0.55) | KMT2AMEN1MMP14POLBMAPT | |
| SCHEMBL11217253 | 0.82 | MAPT (0.58) | KMT2AMEN1MMP14POLBMAPT | |
| SCHEMBL11139038 | 0.81 | MEN1 (0.58) | KMT2AMEN1MMP14MAPTCYP1A2 | |
| SCHEMBL27503938 | 0.81 | MAPT (0.54) | KMT2AMEN1POLBMAPTAPEX1 | |
| SCHEMBL11533589 | 0.79 | CYP1A2 (0.73) | KMT2AMEN1MMP14POLBMAPT | |
| SCHEMBL29074195 | 0.78 | MAOA (0.64) | KMT2AMEN1MMP14POLBMAPT | |
| SCHEMBL9174462 | 0.77 | MAPT (0.66) | KMT2AMEN1POLBMAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859032-B1 | Bridged anthraquinones | BAYER AG (DE) | 2001-11-21 | — | — | EP | disclosed |
| US-5912386-A | Bridged anthraquinones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-15 | — | — | US | disclosed |
| EP-0859032-A1 | Bridged anthraquinones | BAYER AG (DE) | 1998-08-19 | — | — | EP | disclosed |