Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092326 | 0.87 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1MAPTALOX5 | |
| SCHEMBL4623580 | 0.87 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1MAPTALOX5 | |
| SCHEMBL17287255 | 0.86 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1MAPTALOX5 | |
| SCHEMBL10629493 | 0.86 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL17373023 | 0.86 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1MAPTALOX5 | |
| SCHEMBL9715845 | 0.85 | HCAR2 (0.38) | HCAR2AKR1B10AKR1B1MAPTALOX5 | |
| SCHEMBL16205020 | 0.84 | HCAR2 (0.38) | HCAR2AKR1B10AKR1B1MAPTALOX5 | |
| SCHEMBL9764056 | 0.84 | HCAR2 (0.38) | HCAR2AKR1B10AKR1B1MAPTALOX5 | |
| SCHEMBL3310222 | 0.83 | HCAR2 (0.39) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL9715815 | 0.83 | HCAR2 (0.39) | HCAR2AKR1B10AKR1B1MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160295-A1 | Clear coatings, and method of forming multilayer coatings | Nippon Paint Co., Ltd. (JP) | 2001-12-05 | — | — | EP | disclosed |