Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398281 | 0.91 | HCAR2 (0.37) | HCAR2AKR1B10AKR1B1ALOX5MAPT | |
| SCHEMBL9763748 | 0.89 | HCAR2 (0.35) | HCAR2AKR1B10AKR1B1ALOX5MAPT | |
| SCHEMBL9763728 | 0.85 | THRB (0.48) | HCAR2AKR1B10AKR1B1TDP1MAPT | |
| SCHEMBL22092326 | 0.85 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1TDP1ALOX5 | |
| SCHEMBL4623580 | 0.85 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1TDP1ALOX5 | |
| SCHEMBL16205020 | 0.84 | HCAR2 (0.38) | HCAR2AKR1B10AKR1B1TDP1ALOX5 | |
| SCHEMBL7794491 | 0.84 | HCAR2 (0.39) | HCAR2AKR1B10AKR1B1TDP1ALOX5 | |
| SCHEMBL17373023 | 0.83 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1TDP1ALOX5 | |
| SCHEMBL17287255 | 0.83 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1TDP1ALOX5 | |
| SCHEMBL10629493 | 0.83 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1TDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988788-A | Room temperature-curable coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | claimed |