SCHEMBL7794792

SCHEMBL7794792

CC(C)(C)c1cc(CC(=O)O)cc(C2(C)CCCCC2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR Q13258 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 4/20 0.39
GLA P06280 1/20 0.39
ALOX12 P18054 1/20 0.39
GLRA3 O75311 1/20 0.36
GLRB P48167 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
RARB P10826 2/20 0.36
RARG P13631 2/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
ATM Q13315 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792145 0.87 GAA (0.45) PTGDRPTGDR2ALDH1A1KDM4ETDP1
SCHEMBL7940452 0.84 PTGDR (0.41) PTGDRPTGDR2ALDH1A1TDP1TSHR
SCHEMBL7786447 0.82 GLA (0.44) PTGDRPTGDR2TSHRGLAALOX12
SCHEMBL8400750 0.82 ALDH1A1 (0.34) PTGDRPTGDR2ALDH1A1KDM4ETDP1
SCHEMBL7933369 0.81 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1TSHRGLA
SCHEMBL7940089 0.81 TSHR (0.46) PTGDRPTGDR2KDM4ETDP1TSHR
SCHEMBL11806647 0.80 ALDH1A1 (0.40) ALDH1A1KDM4ETDP1TSHRGLA
SCHEMBL11806638 0.80 ALDH1A1 (0.40) ALDH1A1KDM4ETDP1TSHRGLA
SCHEMBL7796578 0.80 RARG (0.47) PTGDRPTGDR2TSHRGLAALOX12
SCHEMBL2908677 0.79 ALDH1A1 (0.40) ALDH1A1KDM4ETDP1TSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed