Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792112 | 0.98 | ALDH1A1 (0.46) | ALDH1A1KCNA3FLT3BCHEACHE | |
| SCHEMBL7792098 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KCNA3MAOBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7786457 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KCNA3MAOBMEN1KMT2A | |
| SCHEMBL7792216 | 0.92 | ALDH1A1 (0.41) | ALDH1A1KCNA3MAOBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7794703 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KCNA3MAOBMEN1KMT2A | |
| SCHEMBL7794717 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KCNA3MAOBKMT2A | |
| SCHEMBL27493230 | 0.90 | HTR2C (0.43) | ALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL7786466 | 0.89 | CYP1A2 (0.42) | ALDH1A1MAOBKMT2A | |
| SCHEMBL7792470 | 0.89 | CYP1A2 (0.42) | ALDH1A1MAOBKMT2A | |
| SCHEMBL7796236 | 0.89 | TTR (0.40) | ALDH1A1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |