Phenol

Phenol

SCHEMBL7794825

C=CC.C=CC.C=CC.C=CC.O=CC(=O)O.Oc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA3 P07451 2/20 0.48
CA4 P22748 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
GLA P06280 1/20 0.48
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 1/20 0.41
CES2 O00748 1/20 0.40
AKT1 P31749 1/20 0.40
ALDH5A1 P51649 1/20 0.39
ABAT P80404 1/20 0.39
ESR1 P03372 3/20 0.38
PKM P14618 2/20 0.38
HCAR2 Q8TDS4 2/20 0.38
TSHR P16473 1/20 0.38
AKR1B10 O60218 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27343404 0.98 TDP1 (0.46) TDP1CA12CA1CA2CA3
Phenol SCHEMBL28063923 0.89 CA12 (0.55) TDP1CA12CA1CA2CA3
Phenol SCHEMBL1008441 0.89 CA1 (0.61) TDP1CA12CA1CA2CA3
Phenol SCHEMBL28125858 0.86 CA12 (0.52) TDP1CA12CA1CA2CA3
Phenol SCHEMBL27927442 0.86 CA1 (0.58) TDP1CA12CA1CA2CA3
Phenol SCHEMBL27356999 0.86 CA1 (0.58) TDP1CA12CA1CA2CA3
Phenol SCHEMBL27623484 0.86 TDP1 (0.58) TDP1CA12CA1CA2CA3
Phenol SCHEMBL28603362 0.86 CA12 (0.65) TDP1CA12CA1CA2CA3
Phenol SCHEMBL7070848 0.86 CA12 (0.65) TDP1CA12CA1CA2CA3
Phenol SCHEMBL7077037 0.86 CA12 (0.65) TDP1CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696635-B1 Two-stroke engine lubricant and method of using same LUBRIZOL CORP (US) 2001-12-12 EP disclosed
EP-0696635-A2 Two-stroke engine lubricant and method of using same THE LUBRIZOL CORPORATION (US) 1996-02-14 EP disclosed