Phenol

Phenol

SCHEMBL1008441

O=CC(=O)O.Oc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.61
CA2 P00918 5/20 0.61
CA4 P22748 4/20 0.61
CA12 O43570 4/20 0.61
CA9 Q16790 4/20 0.61
TDP1 Q9NUW8 3/20 0.61
CA3 P07451 3/20 0.61
CA14 Q9ULX7 3/20 0.61
GLA P06280 1/20 0.61
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 1/20 0.50
CES2 O00748 1/20 0.48
CA6 P23280 3/20 0.44
HCAR2 Q8TDS4 2/20 0.44
PKM P14618 2/20 0.44
TYR P14679 2/20 0.44
CA5A P35218 2/20 0.44
CA7 P43166 2/20 0.44
CA5B Q9Y2D0 2/20 0.44
AKR1B10 O60218 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27927442 0.97 CA1 (0.58) CA1CA2CA4CA12CA9
Phenol SCHEMBL27356999 0.97 CA1 (0.58) CA1CA2CA4CA12CA9
Phenol SCHEMBL7794825 0.89 TDP1 (0.48) CA1CA2CA4CA12CA9
Hydroquinone SCHEMBL28950384 0.88 CA2 (0.54) CA1CA2CA4CA12CA9
Phenol SCHEMBL27343404 0.87 TDP1 (0.46) CA1CA2CA4CA12CA9
Phenol SCHEMBL10385052 0.84 TDP1 (0.55) CA1CA2CA4CA12CA9
Resorcinol SCHEMBL28950381 0.84 ALDH1A1 (0.60) CA1CA2CA12CA9TDP1
Fumaric Acid SCHEMBL10892029 0.83 CA1 (0.61) CA1CA2CA4CA12CA9
Maleic Acid SCHEMBL21816858 0.83 CA1 (0.61) CA1CA2CA4CA12CA9
Fumaric Acid SCHEMBL523843 0.83 CA1 (0.61) CA1CA2CA4CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110112260-A1 COMPOSITION COMPRISING A BLEND OF RESINS DSM IP ASSETS B.V. (NL) 2011-05-12 US claimed
US-20110086988-A1 COMPOSITION COMPRISING POLYOLS EVONIK DEGUSSA GMBH (DE) 2011-04-14 US claimed
EP-2268685-A1 COMPOSITION COMPRISING POLYOLS DSM IP Assets B.V. (NL) 2011-01-05 EP claimed
EP-2268735-A1 COMPOSITION COMPRISING A BLEND OF RESINS DSM IP Assets B.V. (NL) 2011-01-05 EP claimed
CN-100569950-C Fermentative production D-p-hydroxybenzene glycine and D-phenylglycocoll DSM IP ASSETS B V DSM BIOTECH (NL) 2009-12-16 CN claimed
WO-2009115545-A1 COMPOSITION COMPRISING POLYOLS DSM IP ASSETS B.V. (NL) 2009-09-24 WO claimed
WO-2009115544-A1 COMPOSITION COMPRISING A BLEND OF RESINS DSM IP ASSETS B.V. (NL) 2009-09-24 WO claimed
CN-1483080-A Fermentation production of D-p-hydroxyphenylglycine and D-phenylglycine DSM 2004-03-17 CN claimed
US-5112752-A Biocatalytic oxidation using soybean and other legume peroxidases THE MEAD CORPORATION (US) 1992-05-12 US claimed
JP-8060171-A None JP disclosed
CN-111051375-B Method for preparing lignin-modified polyphenol products and use thereof for treating leather and pelts 史密特-费赫特运营有限公司 2024-04-19 CN disclosed
US-11739200-B2 3-phenyl-3H-1-benzofuran-2-one compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2023-08-29 US disclosed
CN-115702223-A Phenolic resin and coating composition using the same PPG工业俄亥俄公司 2023-02-14 CN disclosed
CN-111393276-B Extraction method of natural p-hydroxybenzaldehyde 湖南省农产品加工研究所 2022-12-16 CN disclosed
EP-0594814-A1 METAL CARBOXYLATES OF ALKYLENE BIS-PHENOL ALKONIC ACIDS USEFUL AS ADDITIVES FOR FUELS AND LUBRICANTS. LUBRIZOL CORP (US) 1994-05-04 EP disclosed
EP-0594804-A1 TWO-CYCLE ENGINE LUBRICANT AND METHOD OF USING SAME THE LUBRIZOL CORPORATION (US) 1994-05-04 EP disclosed
US-5281346-A Olefin polymers or oligomers substituted phenol-glycolic acid reaction product THE LUBRIZOL CORPORATION (US) 1994-01-25 US disclosed
WO-1993021143-A1 METAL CARBOXYLATES OF ALKYLENE BIS-PHENOL ALKONIC ACIDS USEFUL AS ADDITIVES FOR FUELS AND LUBRICANTS THE LUBRIZOL CORPORATION (US) 1993-10-28 WO disclosed
WO-1993020698-A1 TWO-CYCLE ENGINE LUBRICANT AND METHOD OF USING SAME THE LUBRIZOL CORPORATION (US) 1993-10-28 WO disclosed
US-4118299-A Electrochemical water desalination process MAGET HENRI JEAN ROBERT 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739200-B2 3-phenyl-3H-1-benzofuran-2-one compounds and compositions comprising the same PAH, TRPV1, CBR1 CA1 2484/4885CA2 1085/4885CA4 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.