SCHEMBL7794926

SCHEMBL7794926

Cc1cc(CCC(=O)O)cc(C(C)(C)CC(C)(C)C)c1O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
KMT2A Q03164 2/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
FFAR4 Q5NUL3 4/20 0.37
MEN1 O00255 1/20 0.37
FFAR1 O14842 4/20 0.36
HMGB1 P09429 1/20 0.36
CXCL12 P48061 1/20 0.36
TBXAS1 P24557 1/20 0.35
ACLY P53396 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11361192 0.91 GAA (0.48) GAANPSR1THRATHRBKMT2A
SCHEMBL5850665 0.87 GAA (0.42) GAANPSR1THRATHRBKMT2A
SCHEMBL7796445 0.87 GAA (0.55) GAANPSR1KMT2ARXRARXRB
SCHEMBL7792782 0.85 HMGB1 (0.38) GAATHRATHRBRXRARXRB
SCHEMBL39866 0.85 GAA (0.55) GAANPSR1THRATHRBKMT2A
Hydrogen Peroxide SCHEMBL28104512 0.85 GAA (0.55) GAANPSR1THRATHRBKMT2A
SCHEMBL29387462 0.85 GAA (0.55) GAANPSR1THRATHRBKMT2A
SCHEMBL7942304 0.84 HSPA5 (0.41) GAANPSR1THRATHRBKMT2A
SCHEMBL7794928 0.84 THRA (0.42) GAANPSR1THRATHRBKMT2A
Methane SCHEMBL28345434 0.84 GAA (0.54) GAANPSR1THRATHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2602300-B1 PHOTOCHROMIC COMPOSITION TOKUYAMA CORP (JP) 2019-06-12 EP disclosed
US-9234984-B2 Photochromic composition TOKUYAMA CORPORATION (JP) 2016-01-12 US disclosed
US-20130215488-A1 Photochromic Composition TOKUYAMA CORPORATION (JP) 2013-08-22 US disclosed
EP-2602300-A1 PHOTOCHROMIC COMPOSITION Tokuyama Corporation (JP) 2013-06-12 EP disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed