Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559618 | 0.94 | MAPT (0.44) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7800644 | 0.90 | RBP4 (0.46) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7794978 | 0.86 | MEN1 (0.45) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL1138208 | 0.86 | CA12 (0.43) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL4928692 | 0.86 | CA12 (0.43) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7800857 | 0.86 | KMT2A (0.42) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL6561048 | 0.85 | MAPT (0.43) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL6559685 | 0.85 | MAPT (0.50) | MAPTKMT2AL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL4928452 | 0.85 | PHGDH (0.41) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL1138146 | 0.84 | MAPT (0.44) | MAPTKMT2AL3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075469-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-02-14 | — | — | EP | disclosed |
| WO-2000052001-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-09-08 | — | — | WO | disclosed |