Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011858 | 0.88 | TLR9 (0.52) | TLR9TDP1EPHX2PSIP1ALDH1A1 | |
| SCHEMBL7011863 | 0.88 | TLR9 (0.52) | TLR9TDP1EPHX2PSIP1ALDH1A1 | |
| SCHEMBL8366438 | 0.83 | TLR9 (0.50) | TLR9TDP1EPHX2PSIP1FAAH | |
| SCHEMBL8366439 | 0.83 | TLR9 (0.50) | TLR9TDP1EPHX2PSIP1FAAH | |
| SCHEMBL6901746 | 0.82 | EPHX2 (0.51) | TLR9TDP1EPHX2PSIP1FAAH | |
| SCHEMBL6901744 | 0.82 | EPHX2 (0.51) | TLR9TDP1EPHX2PSIP1FAAH | |
| SCHEMBL10826201 | 0.78 | TLR9 (1.00) | TLR9TDP1PSIP1ALDH1A1TSHR | |
| SCHEMBL10825832 | 0.78 | TLR9 (1.00) | TLR9TDP1PSIP1ALDH1A1TSHR | |
| SCHEMBL29171177 | 0.73 | TDP1 (0.45) | TLR9TDP1EPHX2PSIP1ALDH1A1 | |
| SCHEMBL6465522 | 0.73 | TLR9 (0.59) | TLR9TDP1PSIP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158995-A1 | BIOLOGICALLY ACTIVE COMPOUNDS OF GANODERMA PFEIFFERI DMS 13239 | Ganomycin Gesellschaft für Biomedizinische Forschung mbH (DE) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000053207-A1 | BIOLOGICALLY ACTIVE COMPOUNDS OF $I(GANODERMA PFEIFFERI) DMS 13239 | GANOMYCIN GESELLSCHAFT FÜR BIOMEDIZINISCHE FORSCHUNG MBH ; (DE) | 2000-09-14 | — | — | WO | disclosed |