Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 9/20 | 0.63 |
| ▸ | RARA | P10276 | 9/20 | 0.63 |
| ▸ | RARB | P10826 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.61 |
| ▸ | IKBKB | O14920 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757395 | 0.87 | RARA (0.75) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL8431773 | 0.84 | RARA (0.81) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL8431769 | 0.84 | RARA (0.81) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL5834539 | 0.84 | RARG (0.56) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL8435247 | 0.83 | CYP3A4 (0.58) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL566894 | 0.82 | CA12 (0.53) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL9123449 | 0.81 | RARG (0.56) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL5834424 | 0.81 | RARG (0.56) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL28598962 | 0.79 | RARG (0.54) | RARGRARARARBMEN1KMT2A | |
| SCHEMBL566680 | 0.79 | RARG (0.66) | RARGRARARARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643701-B1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CT INTERNAT DE RECH S BR DERMA (FR) | 2001-12-05 | — | — | EP | disclosed |
| EP-0643701-A1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-03-22 | — | — | EP | disclosed |
| WO-1992021663-A1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-12-10 | — | — | WO | disclosed |