Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.64 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715940 | 0.93 | TRPV1 (0.66) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL28386231 | 0.89 | CYP3A4 (0.65) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL28400947 | 0.89 | CYP3A4 (0.65) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL57333 | 0.85 | TRPV1 (0.55) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL4558358 | 0.85 | TRPV1 (0.55) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL28894778 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL28904170 | 0.82 | CYP1A2 (0.58) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL28894516 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL14302244 | 0.82 | TRPV1 (0.66) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL12802334 | 0.82 | TRPV1 (0.66) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835233-B1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | NEN LIFE SCIENCE PROD INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5843396-A | Method for stabilizing radiolabeled organic compounds by adding a separate stabilizing compound | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| US-5738836-A | Composition for stabilizing radiolabeled organic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-4411881-A | Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines | NEW ENGLAND NUCLEAR CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |