Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57333 | 0.88 | TRPV1 (0.55) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL4558358 | 0.88 | TRPV1 (0.55) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL16715940 | 0.87 | TRPV1 (0.66) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL8645559 | 0.82 | TRPV1 (0.62) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL7795393 | 0.82 | CYP3A4 (0.64) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL23205718 | 0.81 | CYP3A4 (0.69) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL29382265 | 0.80 | TRPV1 (0.68) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL1585964 | 0.80 | TRPV1 (0.68) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| Vanillyl Alcohol SCHEMBL28864185 | 0.80 | TRPV1 (0.68) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 | |
| Capsaicin SCHEMBL4302468 | 0.79 | TRPV1 (1.00) | TRPV1CYP1A2CYP3A4ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880705-A2 | Brightening and/or colouring composition with improved product sensation | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | disclosed |