Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.46 |
| ▸ | FDPS | P14324 | 4/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092197 | 0.84 | GSR (0.52) | DPP7 | |
| SCHEMBL874554 | 0.84 | GSR (0.52) | DPP7 | |
| SCHEMBL1666692 | 0.82 | GSR (0.50) | DPP7 | |
| SCHEMBL5444478 | 0.82 | GSR (0.50) | DPP7 | |
| Fluoride SCHEMBL11671041 | 0.82 | GSR (0.50) | DPP7 | |
| SCHEMBL27731459 | 0.82 | GSR (0.50) | DPP7 | |
| SCHEMBL11801571 | 0.82 | GSR (0.50) | DPP7 | |
| SCHEMBL8919007 | 0.81 | GSR (0.44) | DPP7 | |
| SCHEMBL7795355 | 0.80 | LPAR5 (0.51) | S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL27579516 | 0.80 | LPAR5 (0.51) | S1PR2S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1086291-C | The primary and secondary neuroprotective effect of flupirtine in neurodegenerative diseases | ASTA MEDICA AG (DE) | 2002-06-19 | — | — | CN | disclosed |
| EP-0716602-B1 | THE PRIMARY AND SECONDARY NEUROPROTECTIVE EFFECT OF FLUPIRTINE IN NEURODEGENERATIVE DISEASES | ASTA MEDICA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| CN-1129399-A | Primary and secondary neuroprotective effects of flupirtine in neurodegenerative diseases | ASTA MEDICA AG (DE) | 1996-08-21 | — | — | CN | disclosed |
| EP-0716602-A1 | THE PRIMARY AND SECONDARY NEUROPROTECTIVE EFFECT OF FLUPIRTINE IN NEURODEGENERATIVE DISEASES | ASTA Medica Aktiengesellschaft (DE) | 1996-06-19 | — | — | EP | disclosed |
| WO-1995005175-A1 | THE PRIMARY AND SECONDARY NEUROPROTECTIVE EFFECT OF FLUPIRTINE IN NEURODEGENERATIVE DISEASES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1995-02-23 | — | — | WO | disclosed |