Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.50 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579516 | 1.00 | LPAR5 (0.51) | LPAR5LPAR3LPAR1P2RY10S1PR2 | |
| SCHEMBL7797100 | 0.88 | LPAR5 (0.46) | LPAR5LPAR3LPAR1P2RY10LPAR2 | |
| SCHEMBL27554230 | 0.85 | P2RY10 (0.45) | LPAR5LPAR3LPAR1P2RY10LPAR2 | |
| SCHEMBL7795517 | 0.80 | LAP3 (0.52) | S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL28954689 | 0.79 | HTT (0.54) | LPAR5LPAR3LPAR1P2RY10PLA2G2C | |
| SCHEMBL7062648 | 0.76 | LPAR3 (0.71) | LPAR5LPAR3LPAR1P2RY10S1PR2 | |
| SCHEMBL25354441 | 0.76 | P2RY10 (0.54) | LPAR5P2RY10PLA2G2CHTTCYP1A2 | |
| SCHEMBL14174568 | 0.76 | ALDH1A1 (0.47) | PLA2G2CHTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL25354445 | 0.76 | P2RY10 (0.54) | LPAR5P2RY10PLA2G2CHTTCYP1A2 | |
| SCHEMBL13937592 | 0.75 | CES2 (0.53) | LPAR5LPAR3LPAR1PLA2G2CHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1328565-A | Antiviral purine derivatives | UNIV CARDIFF (GB) | 2001-12-26 | — | — | CN | disclosed |
| US-20010031745-A1 | Antiviral purine derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031745-A1 | Antiviral purine derivatives | PNP, TYMP, MTAP | LPAR5 1905/4885LPAR3 1997/4885LPAR1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.