SCHEMBL7795595

SCHEMBL7795595

CCOC(=O)CCCOc1cc(C)c(S(=O)(=O)NC(=N)c2ccccc2)c(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
TBXAS1 P24557 3/20 0.38
LTA4H P09960 2/20 0.37
PTPN1 P18031 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
WDR5 P61964 1/20 0.36
F2 P00734 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795478 0.90 MAPT (0.39) L3MBTL1TDP1LTA4HPTPN1MAPT
SCHEMBL7799028 0.85 MAPT (0.37) L3MBTL1LTA4HPTPN1MAPTWDR5
SCHEMBL7795186 0.81 MEN1 (0.38) HPGDALDH1A1GAA
SCHEMBL7795476 0.80 AR (0.35) WDR5F2ALDH1A1
SCHEMBL7799040 0.77 MEN1 (0.43) L3MBTL1PTPN1MAPTHPGDALDH1A1
SCHEMBL29213722 0.68 TDP1 (0.64) TDP1MAPTHPGDALDH1A1
SCHEMBL7795236 0.67 MEN1 (0.40) L3MBTL1TDP1MAPTHPGDALDH1A1
SCHEMBL201784 0.67 MEN1 (0.59) TDP1MAPTALDH1A1GAA
SCHEMBL13244238 0.67 TSHR (0.48) TDP1MAPTWDR5ALDH1A1GAA
SCHEMBL13017224 0.66 F2 (0.47) F2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2001-08-09 US disclosed
US-6225480-B1 FOR SYNTHESIS OF ORGANIC COMPOUNDS CONTAINING--NH--GROUPS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-01 US disclosed
EP-0948480-A1 SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-13 EP disclosed
WO-1998029386-A1 SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis H1-0, H1-2, ASH2L L3MBTL1 567/4885TDP1 2593/4885TBXAS1 2065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.