SCHEMBL7795478

SCHEMBL7795478

CCOC(=O)CCCOc1ccc(C(=N)NS(=O)(=O)c2c(C)cc(OCCCC(=O)O)c(C)c2C)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LTA4H P09960 4/20 0.38
PTPN1 P18031 3/20 0.38
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
BRD4 O60885 1/20 0.37
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
P2RY12 Q9H244 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795595 0.90 L3MBTL1 (0.39) MAPTLTA4HPTPN1L3MBTL1TDP1
SCHEMBL7799028 0.90 MAPT (0.37) MAPTSMN1; SMN2LTA4HPTPN1BRD4
SCHEMBL7795476 0.86 AR (0.35) SMN1; SMN2TSHRFFAR1FFAR4
SCHEMBL7795186 0.77 MEN1 (0.38) SMN1; SMN2BRD4TSHR
SCHEMBL7799040 0.74 MEN1 (0.43) MAPTPTPN1BRD4TSHRL3MBTL1
SCHEMBL7294390 0.68 LTA4H (0.53) MAPTSMN1; SMN2LTA4HL3MBTL1TDP1
SCHEMBL7752657 0.68 PRSS1 (0.61) MAPT
SCHEMBL27543472 0.68 PPARA (0.51) PPARATSHRL3MBTL1FFAR1FFAR4
Iodide SCHEMBL7752650 0.67 PRSS1 (0.59) MAPT
Hydrochloric Acid SCHEMBL7753379 0.67 PPARA (0.50) PPARATSHRL3MBTL1FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2001-08-09 US disclosed
US-6225480-B1 FOR SYNTHESIS OF ORGANIC COMPOUNDS CONTAINING--NH--GROUPS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-01 US disclosed
EP-0948480-A1 SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-13 EP disclosed
WO-1998029386-A1 SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis H1-0, H1-2, ASH2L MAPT 3715/4885SMN1; SMN2 681/4885LTA4H 1359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.