Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.31 |
| ▸ | PRKCG | P05129 | 2/20 | 0.31 |
| ▸ | PRKCB | P05771 | 2/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | PRKCH | P24723 | 2/20 | 0.31 |
| ▸ | PRKCI | P41743 | 2/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807307 | 1.00 | ALDH1A1 (0.42) | ALDH1A1EPHX1PRKD3PRKCGPRKCB | |
| SCHEMBL2462839 | 0.90 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL31541808 | 0.89 | PRKD3 (0.38) | ALDH1A1EPHX1PRKD3PRKCGPRKCB | |
| SCHEMBL15560286 | 0.87 | ALDH1A1 (0.62) | ALDH1A1EPHX1PRKD3PRKCGPRKCB | |
| SCHEMBL19306483 | 0.87 | ALDH1A1 (0.34) | ALDH1A1EPHX1 | |
| SCHEMBL11035529 | 0.87 | ALDH1A1 (0.34) | ALDH1A1EPHX1 | |
| SCHEMBL829693 | 0.87 | ALDH1A1 (0.34) | ALDH1A1EPHX1 | |
| SCHEMBL2102930 | 0.87 | ALDH1A1 (0.62) | ALDH1A1EPHX1PRKD3PRKCGPRKCB | |
| SCHEMBL10514828 | 0.87 | ALDH1A1 (0.62) | ALDH1A1EPHX1PRKD3PRKCGPRKCB | |
| SCHEMBL16510278 | 0.87 | ALDH1A1 (0.34) | ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026947-B1 | COMPOSITION AND METHOD FOR TREATING PENILE ERECTILE DYSFUNCTION | MACROCHEM CORP (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-1026947-A4 | COMPOSITION AND METHOD FOR TREATING PENILE ERECTILE DYSFUNCTION | MACROCHEM CORP (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-1026947-A1 | COMPOSITION AND METHOD FOR TREATING PENILE ERECTILE DYSFUNCTION | MacroChem Corporation (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999065303-A1 | COMPOSITION AND METHOD FOR TREATING PENILE ERECTILE DYSFUNCTION | MACROCHEM CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |
| US-5942545-A | Composition and method for treating penile erectile dysfunction | MACROCHEM CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| US-5527797-A | IONTOPHORESIS | MACROCHEM CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0552879-A1 | Improved iontophoretic administration of drugs | MACROCHEM CORPORATION (US) | 1993-07-28 | — | — | EP | disclosed |
| EP-0268460-B1 | NEW PERCUTANEOUS ABSORPTION ENHANCERS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | Macrochem Corporation (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4861764-A | Percutaneous absorption enhancers, compositions containing same and method of use | MACRO CHEM. CORP. (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0268460-A1 | New percutaneous absorption enhancers, compositions containing same and method of use | Macrochem Corporation (US) | 1988-05-25 | — | — | EP | disclosed |