SCHEMBL7795663

SCHEMBL7795663

CCOC(=O)CC1(C)CCc2c(C)c(S(=O)(=O)NC(=N)c3ccccc3)c(C)c(C)c2O1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PLG P00747 3/20 0.39
PLAU P00749 2/20 0.39
F10 P00742 1/20 0.39
KLKB1 P03952 1/20 0.39
PPARG P37231 1/20 0.36
GAA P10253 2/20 0.35
ALOX5 P09917 2/20 0.34
PSEN1 P49768 5/20 0.33
PTPN1 P18031 1/20 0.33
GSTO1 P78417 1/20 0.33
TTPA P49638 1/20 0.32
F2 P00734 1/20 0.32
ST14 Q9Y5Y6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795590 0.91 PPARG (0.34) PLGPLAUF10KLKB1PPARG
SCHEMBL7799060 0.90 PLG (0.41) PLGPLAUF10KLKB1PPARG
SCHEMBL7788542 0.83 PLG (0.37) PLGPLAUF10KLKB1PPARG
SCHEMBL7797182 0.83 PSEN1 (0.40) PLGPLAUF10KLKB1PPARG
SCHEMBL7795225 0.82 PLG (0.37) PLGPLAUF10KLKB1PPARG
SCHEMBL7795257 0.80 PPARG (0.34) PLGPLAUF10KLKB1PPARG
SCHEMBL7795202 0.78 MEN1 (0.37) ALOX5PSEN1PTPN1GSTO1
SCHEMBL7797943 0.77 PSEN1 (0.35) PLGPLAUF10KLKB1PPARG
SCHEMBL7795661 0.74 PPARG (0.31) PLGPLAUF10KLKB1PPARG
SCHEMBL9816262 0.72 PTGS1 (0.54) ALOX5TTPA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2001-08-09 US disclosed
US-6225480-B1 FOR SYNTHESIS OF ORGANIC COMPOUNDS CONTAINING--NH--GROUPS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-01 US disclosed
EP-0948480-A1 SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-13 EP disclosed
WO-1998029386-A1 SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis H1-0, H1-2, ASH2L PLG 2853/4885PLAU 3178/4885F10 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.