SCHEMBL7795202

SCHEMBL7795202

CCOC(=O)CC1(C)CCc2c(C)c(S(=O)(=O)Cl)c(C)c(C)c2O1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PDE4A P27815 1/20 0.37
PDE3A Q14432 1/20 0.37
GSTO1 P78417 2/20 0.37
PTPN1 P18031 1/20 0.37
PSEN1 P49768 8/20 0.36
ALOX5 P09917 3/20 0.36
NR1I2 O75469 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7799031 0.88 KMT2A (0.32) MEN1KMT2APDE4APDE3AGSTO1
SCHEMBL9816262 0.82 PTGS1 (0.54) MEN1KMT2AALOX5NR1I2PTGS1
SCHEMBL7330589 0.79 MEN1 (0.58) MEN1KMT2APDE4APDE3AGSTO1
SCHEMBL7795663 0.78 PLG (0.39) GSTO1PTPN1PSEN1ALOX5
SCHEMBL7788510 0.78 PSEN1 (0.39) MEN1KMT2APDE4APDE3AGSTO1
SCHEMBL838416 0.75 CYP1A2 (0.39) MEN1KMT2APSEN1PTGS1PTGS2
SCHEMBL29402889 0.75 CYP1A2 (0.39) MEN1KMT2APSEN1PTGS1PTGS2
SCHEMBL5858834 0.74 PPARG (0.40) ALOX5NR1I2
Hydrazine SCHEMBL22634091 0.72 CYP1A2 (0.38) MEN1KMT2APSEN1PTGS1PTGS2
SCHEMBL5860037 0.71 PPARG (0.45) NR1I2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2001-08-09 US disclosed
US-6225480-B1 FOR SYNTHESIS OF ORGANIC COMPOUNDS CONTAINING--NH--GROUPS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012901-A1 Sulphonyl compounds for use as linkers in solid phase and combinatorial synthesis H1-0, H1-2, ASH2L MEN1 1879/4885KMT2A 173/4885PDE4A 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.