Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.60 |
| ▸ | XIAP | P98170 | 11/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791691 | 0.92 | XIAP (0.53) | GHSRXIAPAGTR1 | |
| SCHEMBL7792291 | 0.86 | XIAP (0.56) | GHSRXIAPAGTR1 | |
| SCHEMBL7785833 | 0.86 | GHSR (0.79) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7791800 | 0.85 | GHSR (0.58) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785967 | 0.84 | GHSR (0.67) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL9420850 | 0.83 | GHSR (0.64) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7791736 | 0.82 | GHSR (0.59) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7791949 | 0.82 | GHSR (0.59) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7795979 | 0.81 | GHSR (0.62) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7795829 | 0.80 | GHSR (0.64) | GHSRXIAPAGTR1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | claimed |
| WO-1994005634-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-03-17 | — | — | WO | claimed |