Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Questiomycin B SCHEMBL8379961 | 0.90 | MAPT (0.36) | ESR1ESR2HSD17B10MAPTPOLB | |
| SCHEMBL26037688 | 0.89 | MAPT (0.39) | ESR1ESR2HSD17B10MAPTPOLB | |
| SCHEMBL26037438 | 0.82 | MAPT (0.34) | ESR1ESR2HSD17B10MAPTPOLB | |
| SCHEMBL10013732 | 0.78 | ESR1 (0.39) | ESR1ESR2HSD17B10MAPTPOLB | |
| SCHEMBL7788600 | 0.77 | ESR1 (0.36) | ESR1ESR2HSD17B10MAPTHPGD | |
| SCHEMBL7804231 | 0.75 | HPGD (0.56) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL2129997 | 0.73 | HPGD (0.42) | ESR1ESR2HSD17B10MAPTCA12 | |
| SCHEMBL13843390 | 0.73 | ESR1 (0.49) | ESR1ESR2HSD17B10CA12CA1 | |
| SCHEMBL18879536 | 0.73 | ESR1 (0.49) | ESR1ESR2HSD17B10MAPTHPGD | |
| SCHEMBL7552402 | 0.73 | MAPT (0.35) | MAPTPOLBHSP90AA1KDM4ECRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906903-B1 | Bis-o-amino(thio)phenols and their preparartion | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6150558-A | Bis-o-amino(thio)phenols, and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-11-21 | — | — | US | disclosed |
| EP-0906903-A2 | Bis-o-amino(thio)phenols and their preparartion | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0905169-A2 | Precursors of polybenzoxazoles and polybenzothiazoles | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |