Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406697 | 0.86 | HPGD (0.51) | HPGDHTTHSD17B10CA12CA1 | |
| SCHEMBL19809299 | 0.86 | HPGD (0.51) | HPGDHTTHSD17B10CA12CA1 | |
| SCHEMBL2131590 | 0.84 | HTT (0.46) | HPGDHTTHSD17B10CA12CA1 | |
| SCHEMBL28900663 | 0.79 | CA12 (0.53) | HPGDHTTHSD17B10CA12CA1 | |
| SCHEMBL14005715 | 0.79 | HPGD (0.40) | HPGDHTTHSD17B10ESR1ESR2 | |
| SCHEMBL10013732 | 0.78 | ESR1 (0.39) | HPGDHTTHSD17B10ESR1ESR2 | |
| SCHEMBL26037688 | 0.76 | MAPT (0.39) | HPGDHTTHSD17B10ESR1ESR2 | |
| SCHEMBL6727277 | 0.75 | PARP10 (0.39) | HPGDHTTHSD17B10MEN1LMNA | |
| SCHEMBL31049518 | 0.75 | THRB (0.44) | HPGDHTTESR1PPARGTHRB | |
| SCHEMBL1636048 | 0.74 | PARP15 (0.55) | HPGDHTTHSD17B10ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101213-A1 | HIGHLY WATER-REPELLENT POLYIMIDE FOR COPIER MEMBER, AND POLYAMIC ACID COMPOSITION | NIPPON SHOKUBAI CO, LTD (JP) | 2012-04-26 | — | — | US | disclosed |