Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794764 | 0.94 | USP2 (0.58) | KDM4EPOLBUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7792581 | 0.92 | USP2 (0.54) | KDM4EPOLBUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7786224 | 0.88 | KDM4E (0.53) | KDM4EPOLBDRD1DRD4DRD5 | |
| SCHEMBL9540788 | 0.87 | KDM4E (0.55) | KDM4EPOLBDRD1DRD4DRD5 | |
| SCHEMBL7796098 | 0.86 | L3MBTL1 (0.46) | KDM4EPOLBUSP2MAOBL3MBTL1 | |
| SCHEMBL7795762 | 0.86 | KDM4E (0.55) | KDM4EPOLBDRD1DRD4DRD5 | |
| SCHEMBL7786453 | 0.86 | CYP2D6 (0.56) | KDM4EPOLBDRD1DRD4DRD5 | |
| SCHEMBL7796201 | 0.86 | KDM4E (0.54) | KDM4EPOLBDRD1DRD4DRD5 | |
| SCHEMBL7792459 | 0.86 | KDM4E (0.51) | KDM4EPOLBDRD1DRD4DRD5 | |
| SCHEMBL7792380 | 0.86 | CYP2D6 (0.53) | KDM4EPOLBDRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |