Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798476 | 0.88 | ESR1 (0.43) | MAPTALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL4371377 | 0.84 | TTR (0.37) | MAPTRAB9ANPC1HPGDLMNA | |
| SCHEMBL10709453 | 0.82 | PTGS1 (0.45) | ALDH1A1CA1CA2CA9MAOB | |
| SCHEMBL12853874 | 0.76 | LMNA (0.46) | MAPTALDH1A1LMNACA1CA2 | |
| SCHEMBL8140565 | 0.76 | MAPT (0.48) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL12853933 | 0.76 | CA1 (0.52) | MAPTALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL79678 | 0.74 | CA1 (0.48) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL3786415 | 0.74 | MAPT (0.47) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL11444324 | 0.74 | HPGD (0.39) | MAPTRAB9ANPC1HPGDLMNA | |
| SCHEMBL18758165 | 0.74 | MAPT (0.52) | MAPTRAB9AALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779886-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2001-12-05 | — | — | EP | disclosed |