SCHEMBL7795855

SCHEMBL7795855

CO/C=C(/Oc1ccc(Cl)cc1C=O)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.41
ALDH1A1 P00352 5/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 5/20 0.37
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
KDM4E B2RXH2 5/20 0.37
CTDSP1 Q9GZU7 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
LMNA P02545 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795858 1.00 ERN1 (0.41) ERN1ALDH1A1HPGDMAPTMEN1
SCHEMBL7806111 0.85 MAPT (0.40) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL7806114 0.85 MAPT (0.40) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL7694769 0.83 TSHR (0.44) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL7694770 0.83 TSHR (0.44) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL7803815 0.82 KDM4E (0.43) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL7803816 0.82 KDM4E (0.43) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL7805468 0.81 ABL1 (0.46) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL7795795 0.81 LMNA (0.41) ALDH1A1HPGDMEN1KMT2ALMNA
SCHEMBL7805464 0.81 ABL1 (0.46) ALDH1A1HPGDMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1097117-A2 ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES AVENTIS AGRICULTURE LTD. (GB) 2001-05-09 EP disclosed
WO-2000003975-A2 ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES AVENTIS AGRICULTURE LTD. (GB) 2000-01-27 WO disclosed