SCHEMBL7795997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16742094	0.88	TDP1 (0.66)	TDP1ALDH1A1POLBAPEX1RECQL
	SCHEMBL7798232	0.84	TDP1 (0.42)	TDP1ALDH1A1KDM4EGAAHSD17B10
	SCHEMBL7788801	0.83	TDP1 (0.41)	TDP1ALDH1A1POLBAPEX1RECQL
	SCHEMBL7270775	0.79	HPGD (0.42)	MAPT
	SCHEMBL8131639	0.78	TDP1 (0.56)	TDP1ALDH1A1POLBAPEX1RECQL
	SCHEMBL8690783	0.77	TDP1 (1.00)	TDP1ALDH1A1POLBAPEX1RECQL
	SCHEMBL22662965	0.77	TDP1 (0.55)	TDP1ALDH1A1POLBAPEX1RECQL
	SCHEMBL7795628	0.76	CXCR2 (0.39)	TDP1PTGS2
	SCHEMBL16742113	0.74	TDP1 (0.66)	TDP1ALDH1A1POLBAPEX1RECQL
	SCHEMBL8131638	0.72	TDP1 (0.56)	TDP1ALDH1A1POLBAPEX1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.