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Sugi Predict / Compounds / SCHEMBL7796037

SCHEMBL7796037

SCHEMBL7796037

CCCC(=O)N[C@@H]1CSc2ccccc2N(Cc2ccc(-c3ccccc3CNC(N)=O)cc2)C1=O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 4/20 0.51
▸ F7 P08709 8/20 0.47
▸ F3 P13726 8/20 0.47
▸ XIAP P98170 1/20 0.45
▸ F2 P00734 2/20 0.44
▸ MME P08473 3/20 0.40
▸ ACE P12821 3/20 0.40
▸ AGTR1 P30556 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786012 0.91 GHSR (0.59) GHSRF7F3XIAPF2
SCHEMBL7792504 0.91 GHSR (0.60) GHSRF7F3XIAPF2
SCHEMBL7794541 0.91 GHSR (0.49) GHSRF7F3XIAPF2
SCHEMBL7791888 0.91 GHSR (0.46) GHSRF7F3XIAPF2
SCHEMBL7785733 0.90 GHSR (0.60) GHSRF7F3XIAPF2
SCHEMBL7796021 0.90 GHSR (0.53) GHSRF7F3XIAPF2
SCHEMBL7791816 0.90 GHSR (0.45) GHSRF7F3XIAPF2
SCHEMBL7795578 0.90 GHSR (0.47) GHSRF7F3XIAPF2
SCHEMBL7794624 0.90 GHSR (0.45) GHSRF7F3XIAPF2
SCHEMBL7795973 0.89 GHSR (0.63) GHSRF7F3XIAPF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659179-B1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO INC (US) 2001-11-21 — — EP claimed
EP-0659179-B1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO INC (US) 2001-11-21 — — EP disclosed