Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP1 | O94782 | 1/20 | 0.45 |
| ▸ | USP19 | O94966 | 1/20 | 0.45 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736234 | 0.85 | USP2 (0.48) | NOTUMKDM4EUSP1NPC1RAB9A | |
| SCHEMBL4414123 | 0.85 | KDM4E (0.47) | NOTUMKDM4EUSP1USP19WDR48 | |
| SCHEMBL4037331 | 0.81 | KDM4E (0.69) | KDM4EKDRNPC1RAB9AHPGD | |
| SCHEMBL9755249 | 0.81 | ALDH1A1 (0.50) | NOTUMKDM4EUSP1USP19WDR48 | |
| SCHEMBL7070626 | 0.81 | KDM4E (0.46) | NOTUMKDM4EUSP1USP19WDR48 | |
| SCHEMBL7566190 | 0.81 | NOTUM (0.50) | NOTUMKDM4EUSP1USP19WDR48 | |
| SCHEMBL10908192 | 0.80 | KDM4E (0.71) | KDM4EUSP1USP19WDR48SMN1; SMN2 | |
| SCHEMBL10341496 | 0.79 | ALDH1A1 (0.49) | KDM4EUSP1USP19WDR48NPC1 | |
| SCHEMBL6606425 | 0.79 | KDM4E (0.49) | NOTUMKDM4EKDRNPC1RAB9A | |
| SCHEMBL1079945 | 0.78 | KDM4E (0.44) | KDM4EUSP1USP19WDR48NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123327-A1 | SOLID SUPPORTS CONTAINING SCINTILLANT | The Nottingham Trent University (GB) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000020475-A1 | SOLID SUPPORTS CONTAINING SCINTILLANT | THE NOTTINGHAM TRENT UNIVERSITY (GB) | 2000-04-13 | — | — | WO | disclosed |