Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795964 | 0.98 | HTR2A (0.36) | HTR2AHTR2CHTR2BIKBKBKCNA3 | |
| SCHEMBL7796225 | 0.97 | HTR2A (0.35) | HTR2AHTR2CHTR2BKCNA3IRAK4 | |
| SCHEMBL7792221 | 0.96 | TTR (0.35) | HTR2AHTR2CHTR2BIKBKBKCNA3 | |
| SCHEMBL7796413 | 0.96 | TTR (0.35) | HTR2AHTR2CHTR2BIKBKBKCNA3 | |
| SCHEMBL7795920 | 0.94 | CHRNB4 (0.34) | HTR2AHTR2CHTR2BIKBKBP2RY2 | |
| Hydrochloric Acid SCHEMBL7792171 | 0.93 | CHRNB4 (0.34) | HTR2AHTR2CHTR2BIKBKBP2RY2 | |
| SCHEMBL7795886 | 0.93 | TTR (0.37) | HTR2AHTR2CHTR2BP2RY2TTR | |
| SCHEMBL7792460 | 0.91 | TTR (0.37) | HTR2AHTR2CHTR2BP2RY2TTR | |
| SCHEMBL27493226 | 0.90 | FLT3 (0.33) | HTR2AHTR2CHTR2BIKBKBKCNA3 | |
| SCHEMBL7796125 | 0.90 | TTR (0.37) | HTR2AHTR2CHTR2BP2RY2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |