Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792460 | 0.98 | TTR (0.37) | TTRP2RY2PTPRCHTR2AHTR2C | |
| SCHEMBL7796125 | 0.97 | TTR (0.37) | TTRP2RY2PTPRCHTR2AHTR2C | |
| SCHEMBL7796488 | 0.95 | TTR (0.36) | TTRP2RY2PTPRCHTR2AHTR2C | |
| SCHEMBL7792221 | 0.94 | TTR (0.35) | TTRP2RY2PTPRCHTR2AHTR2C | |
| SCHEMBL7796413 | 0.94 | TTR (0.35) | TTRP2RY2PTPRCHTR2AHTR2C | |
| SCHEMBL7795905 | 0.94 | TTR (0.36) | TTRP2RY2PTPRCHTR2AHTR2C | |
| SCHEMBL7796237 | 0.93 | HTR2A (0.36) | TTRP2RY2HTR2AHTR2CHTR2B | |
| SCHEMBL7795964 | 0.91 | HTR2A (0.36) | TTRP2RY2HTR2AHTR2CHTR2B | |
| SCHEMBL7796225 | 0.90 | HTR2A (0.35) | HTR2AHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL7795780 | 0.89 | PDCD1LG2 (0.35) | P2RY2PDCD1LG2CD274SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |