Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 8/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 8/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796362 | 0.90 | EGLN1 (0.57) | EGLN1CYP1A2CYP2C19CYP2E1CYP2C8 | |
| SCHEMBL7792319 | 0.83 | PIN1 (0.47) | CYP1A2CYP2C19CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL7794739 | 0.81 | HRH4 (0.41) | EGLN1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27989553 | 0.80 | PDGFRB (0.54) | EGLN1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL7794719 | 0.80 | HRH4 (0.40) | EGLN1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7795733 | 0.79 | HCRTR1 (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL4826512 | 0.78 | EGLN1 (0.53) | EGLN1CYP1A2CYP2C19CYP2E1CYP2C8 | |
| SCHEMBL5952797 | 0.78 | MEN1 (0.50) | EGLN1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL7792330 | 0.78 | HCRTR1 (0.44) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5952886 | 0.78 | EGLN1 (0.50) | EGLN1CYP1A2CYP2C19CYP2E1CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |