Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440048 | 1.00 | EP300 (0.43) | EP300HPSEALDH1A1HTR7CDC25A | |
| SCHEMBL1863216 | 1.00 | EP300 (0.43) | EP300HPSEALDH1A1HTR7CDC25A | |
| SCHEMBL10609651 | 1.00 | EP300 (0.43) | EP300HPSEALDH1A1HTR7CDC25A | |
| SCHEMBL15841884 | 1.00 | EP300 (0.43) | EP300HPSEALDH1A1HTR7CDC25A | |
| SCHEMBL15841989 | 1.00 | EP300 (0.43) | EP300HPSEALDH1A1HTR7CDC25A | |
| SCHEMBL8441598 | 1.00 | EP300 (0.43) | EP300HPSEALDH1A1HTR7CDC25A | |
| SCHEMBL1858950 | 0.90 | KDM4E (0.41) | ALDH1A1HTR7MEN1MAPTKMT2A | |
| SCHEMBL28054185 | 0.89 | KDM4E (0.40) | ALDH1A1HTR7MEN1MAPTKMT2A | |
| SCHEMBL28979721 | 0.86 | CDC25A (0.46) | HPSEHTR7CDC25AOXER1ICMT | |
| SCHEMBL28979704 | 0.86 | CDC25A (0.46) | HPSEHTR7CDC25AOXER1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775215-B1 | CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES OR THIOINDOXYL SUBSTRATES | MEDILITE DIAGNOSTIKA (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-0775215-A1 | CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES | MEDILITE DIAGNOSTIKA (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5589328-A | CHEMICAL INTERMEDIATES OR METABOLITES FOR IMMUNOASSAY | MEDILITE DIAGNOSTIKA | 1996-12-31 | — | — | US | disclosed |
| WO-1996004400-A1 | CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES | MEDILITE DIAGNOSTIKA (US) | 1996-02-15 | — | — | WO | disclosed |
| US-5354655-A | Method for determining the presence or concentration of a bound enzyme | BIOCONTROL SYSTEMS, INC. (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0335354-A2 | Rapid and sensitive low pressure enzyme detection and measurement system | BioControl Systems, Incorporated (US) | 1989-10-04 | — | — | EP | disclosed |