Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054185 | 0.98 | KDM4E (0.40) | KDM4EALDH1A1CREBBPTSHRNR4A2 | |
| SCHEMBL15841989 | 0.90 | EP300 (0.43) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL8441598 | 0.90 | EP300 (0.43) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL8440048 | 0.90 | EP300 (0.43) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL1863216 | 0.90 | EP300 (0.43) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL10609651 | 0.90 | EP300 (0.43) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL15841884 | 0.90 | EP300 (0.43) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL7796491 | 0.90 | EP300 (0.43) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL6421358 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1CREBBPNR4A2GAA | |
| SCHEMBL28948106 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1CREBBPNR4A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674603-B2 | Microorganism detector | PRAIL PRICE RICHARDSON DIAGNOSTICS LIMITED (GB) | 2010-03-09 | — | — | US | claimed |
| EP-1697537-B1 | MICROORGANISM DETECTOR | PRAIL PRICE RICHARDSON DIAGNOS (GB) | 2007-06-13 | — | — | EP | claimed |
| US-20070117172-A1 | Microorganism detector | PRAIL PRICE RICHARDSON DIAGNOSTICS LIMITED (GB) | 2007-05-24 | — | — | US | claimed |
| EP-1697537-A1 | MICROORGANISM DETECTOR | Prail Price Richardson Diagnostics Limited (GB) | 2006-09-06 | — | — | EP | claimed |
| WO-2005061723-A1 | MICROORGANISM DETECTOR | PRAIL PRICE RICHARDSON DIAGNOSTICS LIMITED (GB) | 2005-07-07 | — | — | WO | claimed |
| US-6004769-A | COMPOSITIONS AND PROCEDURES FOR THE DETERMINATION OF HYDROLYTIC ENZYMES IN LIQUID SAMPLES WITH THE AID OF INDOXYL COMPOUNDS AND OXIDIZING AGENTS | MERCK PATENT GESELLSCHAFT (DE) | 1999-12-21 | — | — | US | claimed |
| US-5370994-A | Applying solution containing urea, pH-dependent reducing agent and tetrazolium salt which will be reduced to colored formazan dye(if urea is present) to support containing adsorbed urease | BECTON, DICKINSON AND COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| US-5328831-A | Substrate composition for solid phase urease immunoassay | BECTON, DICKINSON AND COMPANY (US) | 1994-07-12 | — | — | US | claimed |
| US-20240309074-A1 | ENGINEERED MICROBE-TARGETING MOLECULES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-09-19 | — | — | US | disclosed |
| CN-108289928-B | Improved microorganism-binding molecules and uses thereof | 哈佛大学校长及研究员协会 | 2024-09-17 | — | — | CN | disclosed |
| US-11939608-B2 | Engineered heme-binding compositions and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2024-03-26 | — | — | US | disclosed |
| EP-3912986-B1 | CRP CAPTURE/DETECTION OF BACTERIA | HARVARD COLLEGE (US) | 2023-12-13 | — | — | EP | disclosed |
| US-11807677-B2 | Microbe-binding molecules and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-07 | — | — | US | disclosed |
| US-11795212-B2 | Engineered microbe-targeting molecules and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-24 | — | — | US | disclosed |
| EP-0458231-A1 | Substrate composition, immunoassay and urea determination employing immobilized urease | Becton, Dickinson and Company (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0158204-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, CONTAINING A ZWITTERION COUPLING AGENT | MILES INC. (US) | 1989-11-23 | — | — | EP | disclosed |
| US-4835099-A | Signal enhancement in immunoassay by modulation of enzymatic catalysis | BECTON, DICKINSON AND COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0271731-A2 | Signal enhancement in immunoassay by inhibition of enzymatic catalysis | Becton, Dickinson and Company (US) | 1988-06-22 | — | — | EP | disclosed |
| US-4637979-A | Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent | MILES LABORATORIES, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0158204-A2 | Composition and test device for determining the presence of leukocytes, containing a zwitterion coupling agent | MILES INC. (US) | 1985-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939608-B2 | Engineered heme-binding compositions and uses thereof | MB, MYOF, HMBS | KDM4E 3522/4885ALDH1A1 3726/4885CREBBP 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.