SCHEMBL7796812

SCHEMBL7796812

CC(C)(CCO)SCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
PRMT1 Q99873 1/20 0.61
TDP1 Q9NUW8 2/20 0.40
IDO1 P14902 3/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TAAR1 Q96RJ0 2/20 0.36
SLC6A2 P23975 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CYP2C19 P33261 1/20 0.35
GAA P10253 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2655561 0.82 CYP1A2 (0.59) CYP2D6CYP1A2CYP3A4PRMT1TDP1
SCHEMBL6832085 0.82 CYP3A4 (0.46) CYP2D6CYP1A2CYP3A4PRMT1TDP1
SCHEMBL6429213 0.80 CYP1A2 (0.47) CYP2D6CYP1A2CYP3A4PRMT1TSHR
SCHEMBL20425216 0.79 IDO1 (0.47) CYP2D6CYP1A2CYP3A4PRMT1IDO1
SCHEMBL13348421 0.79 CYP2D6 (0.46) CYP2D6CYP1A2CYP3A4PRMT1TDP1
SCHEMBL12879664 0.78 CYP2D6 (0.68) CYP2D6CYP1A2CYP3A4PRMT1IDO1
SCHEMBL2656196 0.77 CYP3A4 (0.41) CYP2D6CYP1A2CYP3A4PRMT1TDP1
SCHEMBL6447334 0.77 CYP1A2 (0.43) CYP2D6CYP1A2CYP3A4PRMT1TDP1
SCHEMBL1654642 0.76 CYP1A2 (1.00) CYP2D6CYP1A2CYP3A4PRMT1IDO1
SCHEMBL11188983 0.76 CYP2D6 (0.66) CYP2D6CYP1A2CYP3A4PRMT1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017136769-A1 PEPTIDE DRUG CONJUGATES EISAI R&D MANAGEMENT CO., LTD. (JP) 2017-08-10 WO disclosed
WO-2017136769-A1 PEPTIDE DRUG CONJUGATES EISAI R&D MANAGEMENT CO., LTD. (JP) 2017-08-10 WO disclosed
JP-2001335557-A NEW METHOD FOR PRODUCING 3-MERCAPTO-3-METHYL-1-BUTANOL AND INTERMEDIATE THEREFOR SANEI GEN FFI INC 2001-12-04 JP disclosed