Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798375 | 0.93 | ALDH1A1 (0.53) | RARBSMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL7799503 | 0.90 | RARB (0.71) | RARBSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7800795 | 0.89 | RARB (0.73) | RARBSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7800799 | 0.89 | RARB (0.73) | RARBSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7796753 | 0.89 | RARB (0.73) | RARBSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL8131697 | 0.87 | RARB (0.75) | RARBSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7798318 | 0.87 | RARB (0.55) | RARBSMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL7789745 | 0.84 | RARB (0.59) | RARBSMN1; SMN2RAB9ANPC1TP53 | |
| Acetic Acid SCHEMBL9272786 | 0.83 | RARB (0.57) | RARBSMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL7798474 | 0.83 | ALDH1A1 (0.68) | RARBSMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160242-A1 | Aromatic fatty acid esters | Rolic AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| EP-0992498-A1 | Aromatic fatty acid esters | Rolic AG (CH) | 2000-04-12 | — | — | EP | disclosed |
| US-5393458-A | Aromatic esters and liquid crystal mixtures containing same | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5326498-A | Electrooptics, ferroelectricity | HOFFMANN-LA ROCHE INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0546298-A2 | Fatty acids esters containing a pyridine or pyrimidine ring as components liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |