Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902963 | 0.87 | EPHX1 (0.45) | LMNAEPHX1SPHK1FDPSSMPD1 | |
| SCHEMBL23130425 | 0.87 | EPHX1 (0.45) | LMNAEPHX1SPHK1FDPSSMPD1 | |
| SCHEMBL9798469 | 0.87 | EPHX1 (0.45) | LMNAEPHX1CYP2D6SPHK1GMNN | |
| SCHEMBL23129956 | 0.87 | EPHX1 (0.45) | LMNAEPHX1SPHK1FDPSSMPD1 | |
| SCHEMBL18837643 | 0.85 | EPHX1 (0.46) | LMNAEPHX1CYP2D6SPHK1GMNN | |
| SCHEMBL18837634 | 0.85 | EPHX1 (0.46) | LMNAEPHX1CYP2D6SPHK1GMNN | |
| SCHEMBL18837636 | 0.85 | EPHX1 (0.46) | LMNAEPHX1CYP2D6SPHK1GMNN | |
| SCHEMBL18837599 | 0.85 | EPHX1 (0.46) | LMNAEPHX1CYP2D6SPHK1GMNN | |
| SCHEMBL26351182 | 0.84 | EPHX1 (0.42) | LMNAEPHX1MAPTFDPSSMPD1 | |
| SCHEMBL18699066 | 0.83 | EPHX1 (0.42) | LMNAEPHX1SPHK1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177469-B1 | ANTIUTOR AGENTS; AUTOIMMUNE DISEASES | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2001-01-23 | — | — | US | claimed |
| EP-0854708-B1 | LIPID ALCOHOLS AS NEW IMMUNOSUPPRESSIVE AND ANTIVIRAL DRUGS | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6177469-B1 | ANTIUTOR AGENTS; AUTOIMMUNE DISEASES | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2001-01-23 | — | — | US | disclosed |
| EP-0854708-A1 | LIPID ALCOHOLS AS NEW IMMUNOSUPPRESSIVE AND ANTIVIRAL DRUGS | Roche Diagnostics GmbH (DE) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997014410-A1 | LIPID ALCOHOLS AS NEW IMMUNOSUPPRESSIVE AND ANTIVIRAL DRUGS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-04-24 | — | — | WO | disclosed |
| EP-0506704-B1 | USE OF ALKYL PHOSPHOLIPIDS AS ANTIVIRAL DRUGS, AS WELL AS NEW COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0506704-A1 | USE OF ALKYL PHOSPHOLIPIDS AS ANTIVIRAL DRUGS, AS WELL AS NEW COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991009602-A2 | USE OF ALKYL PHOSPHOLIPIDS AS ANTIVIRAL DRUGS, AS WELL AS NEW COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-11 | — | — | WO | disclosed |