Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18837636 | 1.00 | EPHX1 (0.46) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL18837634 | 1.00 | EPHX1 (0.46) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL18837599 | 1.00 | EPHX1 (0.46) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL6993726 | 0.91 | ALDH1A1 (0.39) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL9798469 | 0.89 | EPHX1 (0.45) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL28303918 | 0.86 | EPHX1 (0.47) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL13361604 | 0.86 | EPHX1 (0.47) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL7797214 | 0.85 | LMNA (0.50) | EPHX1LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL10628579 | 0.84 | EPHX1 (0.43) | EPHX1LMNAHSD17B10TSHRGMNN | |
| SCHEMBL7800336 | 0.82 | EPHX1 (0.42) | EPHX1LMNAALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053449-B2 | Thioether-containing phenolic compounds | THE LUBRIZOL CORPORATION (US) | 2021-07-06 | — | — | US | disclosed |
| EP-3374478-B1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | LUBRIZOL CORP (US) | 2021-01-06 | — | — | EP | disclosed |
| US-20200239805-A1 | THIOETHER-CONTAINING PHENOLIC COMPOUNDS | THE LUBRIZOL CORPORATION | 2020-07-30 | — | — | US | disclosed |
| EP-3374478-A1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | The Lubrizol Corporation (US) | 2018-09-19 | — | — | EP | disclosed |
| WO-2017083243-A1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | THE LUBRIZOL CORPORATION (US) | 2017-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053449-B2 | Thioether-containing phenolic compounds | TST, TH, COMT | EPHX1 628/4885LMNA 4850/4885ALDH1A1 192/4885 |
| US-20200239805-A1 | THIOETHER-CONTAINING PHENOLIC COMPOUNDS | TST, TH, COMT | EPHX1 628/4885LMNA 4850/4885ALDH1A1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.