Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560524 | 0.87 | NPSR1 (0.41) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL7797401 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7797328 | 0.80 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7133628 | 0.78 | SMN1; SMN2 (0.42) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6559153 | 0.78 | NPSR1 (0.53) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL7797331 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL1088391 | 0.75 | MEN1 (0.53) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL16731837 | 0.74 | MEN1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6559200 | 0.74 | CYP3A4 (0.39) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7131067 | 0.72 | MEN1 (0.39) | MEN1KMT2AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |