Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164968 | 1.00 | MEN1 (0.39) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9223463 | 0.92 | MEN1 (0.45) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL2363026 | 0.91 | MEN1 (0.42) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6673254 | 0.89 | ENPP2 (0.40) | CNR2TRPV1EPHX2ENPP2 | |
| SCHEMBL7768310 | 0.89 | ENPP2 (0.40) | CNR2TRPV1EPHX2ENPP2 | |
| SCHEMBL7794520 | 0.88 | MEN1 (0.49) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7794515 | 0.88 | MEN1 (0.49) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL19371256 | 0.86 | — | — | |
| SCHEMBL6949117 | 0.86 | RECQL (0.41) | LPAR1LPAR3RECQLTRPV1GLA | |
| SCHEMBL3371265 | 0.86 | RECQL (0.41) | LPAR1LPAR3RECQLTRPV1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704522-B1 | Dryer-activated fabric conditioning compositions containing unsaturated fatty acid | PROCTER & GAMBLE (US) | 2001-11-28 | — | — | EP | claimed |
| EP-0704522-A2 | Dryer-activated fabric conditioning compositions containing unsaturated fatty acid | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-03 | — | — | EP | claimed |
| US-5503756-A | ALSO CONTAINING FABRIC SOFTENER CONSISTING OF BIODEGRADABLE QUATERNARY AMMONIUM COMPOUND, ALKOXYLATED SUGAR DERIVATIVE HAVING LONG HYDROPHOBIC GROUP, CARBOXYLIC ACID SALT OF TERTIARY AMINE | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-02 | — | — | US | claimed |