Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGAV | P06756 | 5/20 | 0.40 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602310 | 0.83 | KCNH2 (0.55) | APPPDE10AKCNH2SCN5ANCF1 | |
| SCHEMBL1815740 | 0.82 | APP (0.53) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL6220219 | 0.82 | APP (0.53) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL852472 | 0.82 | APP (0.53) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL14103940 | 0.80 | APP (0.48) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL2522650 | 0.80 | KCNH2 (0.67) | KCNH2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30336032 | 0.79 | APP (0.55) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL19514887 | 0.79 | APP (0.55) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL12705275 | 0.79 | APP (0.80) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL20971411 | 0.78 | APP (0.47) | APPPDE10AKCNH2SCN5AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368566-B2 | Process and intermediates for preparing benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |