Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGAV | P06756 | 7/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336032 | 0.89 | APP (0.55) | APPPDE10AHRH1KCNH2SCN5A | |
| SCHEMBL19514887 | 0.89 | APP (0.55) | APPPDE10AHRH1KCNH2SCN5A | |
| SCHEMBL29907615 | 0.84 | APP (0.47) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL5631959 | 0.84 | APP (0.47) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL7797589 | 0.82 | APP (0.54) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL852472 | 0.81 | APP (0.53) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL6220219 | 0.81 | APP (0.53) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL522064 | 0.79 | HRH1 (0.56) | HRH1KCNH2TAAR1NOS1NOS2 | |
| SCHEMBL12705275 | 0.78 | APP (0.80) | APPPDE10AKCNH2SCN5AITGB3 | |
| SCHEMBL6602310 | 0.78 | KCNH2 (0.55) | APPPDE10AKCNH2SCN5ANCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488513-B1 | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases | AC IMMUNE SA (CH) | 2017-12-27 | — | — | EP | disclosed |
| WO-2011060394-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060394-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060395-A1 | CYCLIC UREAS USEFUL AS HIV INHIBITORS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060395-A1 | CYCLIC UREAS USEFUL AS HIV INHIBITORS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |